Variability in blood alcohol concentrations. Implications for estimating individual results.

نویسندگان

  • B O'Neill
  • A F Williams
  • K M Dubowski
چکیده

In a carefully controlled drinking situation there was great individual variation in peak blood alcohol concentrations (BACS) for given doses of alcohol. Alcohol nomograms and tables based on average results from such studies could be misleading since they could frequently result in serious underestimates or overestimates of peak BACS.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Absorption, distribution and elimination of alcohol: highway safety aspects.

Key aspects of the pharmacokinetics of alcohol are highly relevant to highway safety. Of particular pertinence are the partition of alcohol between various body tissues and fluids and the resulting alcohol concentration ratios for blood: breath and other body fluids, as well as the irregularity and short-term fluctuations of the blood and breath alcohol curves. Most alcohol pharmacokinetics par...

متن کامل

The Motivational Model of Alcohol Abuse: Implications for Prognosis, Prevention and Treatment Programs

Growing number of evidence indicates that individuals' motivational structure - the patterning of an individual's way of relating to goals - plays an important role in increasing the risk of alcohol use. Adaptive motivational structure which includes pursuit of important, subjectively attainable, alcohol-unrelated goals is inversely related to substance use. The strength of this relationship in...

متن کامل

Pharmacokinetic/Pharmacodynamic (PK/PD) Relationship-based Approach to Understand the Variability of Central Neurological Effects of Ethanol

Pharmacokinetic/pharmacodynamic (PK/PD) relationships describe the quantitative relationships between the drug-induced effects and the concurrent corresponding drug concentrations in an individual. Since a long time, rough qualitative relationships have been described between neurological presentation and plasma ethanol concentration in acute ethanol ingestion. However, to date, precise quantit...

متن کامل

A Review on Therapeutic Drug Monitoring of Immunosuppressant Drugs

Immunosuppressants require therapeutic drug monitoring because of their narrow therapeutic index and significant inter-individual variability in blood concentrations. This variability can be because of factors like drug-nutrient interactions, drug-disease interactions, renal-insufficiency, inflammation and infection, gender, age, polymorphism and liver mass. Drug monitoring is widely practiced ...

متن کامل

Cannabis effects on driving lateral control with and without alcohol.

BACKGROUND Effects of cannabis, the most commonly encountered non-alcohol drug in driving under the influence cases, are heavily debated. We aim to determine how blood Δ(9)-tetrahydrocannabinol (THC) concentrations relate to driving impairment, with and without alcohol. METHODS Current occasional (≥1×/last 3 months, ≤3days/week) cannabis smokers drank placebo or low-dose alcohol, and inhaled ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Journal of studies on alcohol

دوره 44 2  شماره 

صفحات  -

تاریخ انتشار 1983